Centre J.D. MacLean pour maladies tropicales - agrégateur /tropmed/fr/aggregator Centre J.D. MacLean pour maladies tropicales - flux agrégés fr Recent publications from TDC/Clinical Epidemiology authors: Malaria https://pubmed.ncbi.nlm.nih.gov/40768732/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250807001859&v=2.18.0.post9+e462414 No abstract Wed, 06 Aug 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Measles Importations by International Travelers, GeoSentinel 2019-2025 https://pubmed.ncbi.nlm.nih.gov/40738382/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250731021112&v=2.18.0.post9+e462414 CONCLUSIONS: Against a background of increasing numbers of measles cases and outbreaks globally, GeoSentinel observed a stable trend of measles importations by international travelers. Measles caused considerable morbidity among travelers. Immunization effectively prevents measles in more than 97% of individuals. Pretravel consultations provide an important opportunity to promote vaccination coverage for all vaccine-preventable diseases, including measles. Wed, 30 Jul 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Impacted subglottic fish vertebra in an infant: an unusual case report https://pubmed.ncbi.nlm.nih.gov/40727513/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250730011515&v=2.18.0.post9+e462414 Inhalation of foreign bodies, a common occurrence in children, can be life-threatening. Different types of foreign bodies can be found, but laryngeal localization is rare. We here report the case of an 8-month-old male infant who presented with respiratory distress, dysphonia, and stridor. On admission, the child exhibited severe laryngeal dyspnea. Cervical CT scan revealed a radiopaque foreign body in the larynx. Endoscopic extraction revealed an impacted fish vertebra in the subglottis.... Tue, 29 Jul 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Integrative Modeling of Urinary Metabolomics and Metal Exposure Reveals Systemic Impacts of Electronic Waste in Exposed Populations https://pubmed.ncbi.nlm.nih.gov/40710556/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250727004612&v=2.18.0.post9+e462414 Background: Informal electronic waste (e-waste) recycling practices release a complex mixture of pollutants, particularly heavy metals, into the environment. Chronic exposure to these contaminants has been linked to a range of health risks, but the molecular underpinnings remain poorly understood. In this study, we investigated the alterations in metabolic profiles due to e-waste exposure and linked these metabolites to systemic biological effects. Methods: We applied untargeted high-resolution... Fri, 25 Jul 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Early-life RSV infection modulates innate immune events, preferentially enhancing allergen-induced type 2 lung inflammation in females https://pubmed.ncbi.nlm.nih.gov/40690502/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250722003841&v=2.18.0.post9+e462414 Respiratory syncytial virus (RSV) causes millions of hospitalizations and thousands of deaths per year globally. Early-life RSV infection is also associated with the subsequent development of wheezing and asthma, which exhibits sex-related disparities in incidence, epidemiology, and morbidity. The mechanisms that underlie these sex-specific effects are not clear. We have developed a combined infection-allergy model in which 10-day old mice are infected with RSV and subsequently exposed to a... Mon, 21 Jul 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Canadian Antibiotic Prescribing for Sepsis (CAPS) Study: A <em>Post Hoc</em> Analysis of the FABLED Cohort Study https://pubmed.ncbi.nlm.nih.gov/40672715/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250718005619&v=2.18.0.post9+e462414 CONCLUSIONS: Empiric therapies for septic patients in Canada were overly broad given the rare isolation of drug-resistant pathogens. Though likely confounded by severity of illness, optimal outcomes were observed when therapy was appropriate relative to the causative pathogen and infectious focus. Thu, 17 Jul 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Severe Malaria in Travelers-Time to Create a Specific Definition https://pubmed.ncbi.nlm.nih.gov/40667864/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250717010041&v=2.18.0.post9+e462414 No abstract Wed, 16 Jul 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Perceptions about hepatitis C and barriers and enablers to screening and treatment among Egyptian immigrants to Canada: a theory-informed qualitative study https://pubmed.ncbi.nlm.nih.gov/40646616/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250713014927&v=2.18.0.post9+e462414 CONCLUSION: There is an urgent need to improve access to care for immigrants from endemic countries to eliminate HCV in Canada. We took a systematic, theory-informed approach to understand lived experiences and views among Egyptian immigrants in Canada. We identified key factors contributing to the low uptake of HCV screening and treatment. These findings will inform a theory-based intervention to optimize HCV care in immigrant communities. Fri, 11 Jul 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Development of machine learning prediction models for systemic inflammatory response following controlled exposure to a live attenuated influenza vaccine in healthy adults using multimodal wearable biosensors in Canada: a single-centre, prospective... https://pubmed.ncbi.nlm.nih.gov/40610361/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250704002539&v=2.18.0.post9+e462414 BACKGROUND: Presymptomatic or asymptomatic immune system signals and subclinical physiological changes might provide a more objective measure of early viral upper respiratory tract infections (VRTIs) compared with symptom-based detection. We aimed to use multimodal wearable sensors, host-response biomarkers, and machine learning to predict systemic inflammation following controlled exposure to a live attenuated influenza vaccine, without relying on symptoms. Thu, 03 Jul 2025 06:00:00 -0400 Recent publications from TDC/Clinical Epidemiology authors: Multiple anthelmintic drug resistance in the canine hookworm Ancylostoma caninum: AAVP position paper and research needs https://pubmed.ncbi.nlm.nih.gov/40596793/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250703013050&v=2.18.0.post9+e462414 Cases of infection with the canine hookworm Ancylostoma caninum that are resistant to all anthelmintic classes registered in the United States of America (USA) for control of this parasite in dogs were first reported in 2019. Termed Multiple Anthelmintic Drug Resistance (MADR), cases have subsequently been reported in pet dogs across the USA. Recent studies using molecular tests that detect mutations known to cause resistance to benzimidazole anthelmintics have revealed an alarming frequency of... Wed, 02 Jul 2025 06:00:00 -0400