Leo Liu
Academic title(s):
Assistant Professor, Department of Microbiology and Immunology
Department:
Microbiology and Immunology
Area(s):
Infectious Diseases
Virology
Current research:
My laboratory is interested in understanding the fundamental innate immune sensing mechanisms and their interplay with viral pathogens. We use RIG-I-like receptors and respiratory RNA viruses, particularly influenza A virus and coronaviruses, as models to discover new players in pattern recognition and regulation of antiviral innate immunity. We leverage state-of-the-art experimental approaches that combine genome-wide phenotypic screens, reverse genetics, and animal models to dissect the host-virus interface at a molecular level. Our ultimate goal is to achieve bench-to-bedside translation of innovative antiviral therapies and vaccines.
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