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DESCRIPTION:Interpreting the Mechanisms and Meaning of Human MEG/EEG signal
 s with the Human Neocortical Neurosolver (HNN) Neural Modeling Software\n
 \nStephanie Jones\, Brown University \n	Tuesday January 23\, 12-1pm\n	Zoom L
 ink: https://mcgill.zoom.us/j/86855481591\n	In Person: 550 Sherbrooke\, Roo
 m 189\n	\n	Abstract: Electro- and magneto-encephalography (EEG/MEG) are the 
 leading methods to non-invasively record human neural dynamics with millis
 econd temporal resolution. However\, it can be extremely difficult to infe
 r the underlying cellular and circuit level origins of these macro-scale s
 ignals without simultaneous invasive recordings. This limits the translati
 on of E/MEG into novel principles of information processing\, or into new 
 treatment modalities for neural pathologies. To address this need\, we dev
 eloped the Human Neocortical Neurosolver (HNN: https://hnn.brown/edu )\, a
  user-friendly neural modeling tool designed to help researchers and clini
 cians interpret human imaging data. A unique feature of HNN’s model is tha
 t it accounts for the biophysics generating the primary electric currents 
 underlying EEG/MEG with enough detail to connect to cell and circuit level
  phenomena that can be studied with invasive techniques in animal models. 
 HNN is being constructed with workflows of use to study some of the most c
 ommonly measured E/MEG signals including event related potentials\, and lo
 w frequency brain rhythms. In this talk\, I will give an overview of the t
 heory behind the development of this neural modeling tool and demonstrate 
 its use in uncovering the mechanisms and meaning of sensory evoked signals
  in primary sensory neocortex and of the influence of prestimulus oscillat
 ory activity on sensory processing. I’ll highlight our studies investigati
 ng the role of 15-29Hz beta frequency activity on somatosensory processing
 . I will also briefly describe other HNN applications including studies of
  Aging and Alzheimer’s disease. Overall\, HNN provides a novel inferential
  tool for translational neuroscience discovery.\n
DTSTART:20240123T170000Z
DTEND:20240123T180000Z
LOCATION:CA\, QC
SUMMARY:QLS Seminar Series - Stephanie Jones
URL:/qls/channels/event/qls-seminar-series-stephanie-j
 ones-353909
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