BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20251006T022238EDT-8890KafMHs@132.216.98.100 DTSTAMP:20251006T062238Z DESCRIPTION:DNA methylation is a critical epigenetic mark which mediates tr anscriptional silencing. During early embryonic development\, correct patt erning of DNA methylation is essential to prevent the expression of transp osons or lineage-inappropriate genes. We have identified a transcriptional corepressor called ZMYM2 which alters the chromatin environment to allow methylation and repression of germline genes and transposons in somatic li neages. We have also found evidence indicating that differences in underly ing chromatin explain both how and why the developing embryo and placenta develop strongly distinct patterns of DNA methylation\n\n \n\nThis seminar will take place in-person and online ( details in attached poster below. All are welcome!\n DTSTART:20240112T160000Z DTEND:20240112T170000Z LOCATION:Room 1034\, McIntyre Medical Building\, CA\, QC\, Montreal\, H3G 1 Y6\, 3655 promenade Sir William Osler SUMMARY:Physiology Seminar: Dr. William Pastor\, 'Factors governing the est ablishment of the embryonic and placental epigenomes' URL:/physiology/channels/event/physiology-seminar-dr-w illiam-pastor-factors-governing-establishment-embryonic-and-placental-3536 65 END:VEVENT END:VCALENDAR