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UID:20250517T061014EDT-7882NvWEE4@132.216.98.100
DTSTAMP:20250517T101014Z
DESCRIPTION:Alessandro Gozzi\n\nSenior Scientist\, Istituto Italiano di Tec
 nologia\, Italy\n\nBio: After receiving a master degree in Biotechnology a
 t the University of Verona (Italy) in 1998\, Alessandro joined the neurosc
 ience centre of GlaxoSmithKline (GSK)\, a research-based pharmaceutical co
 mpany based in Verona (Italy) and Harlow (UK). There he pioneered the use 
 of functional magnetic resonance imaging (fMRI) in rodents to describe the
  neural substrates modulated by pharmacological agents\, a line of researc
 h that he also pursued to obtain a PhD degree in biomedical imaging with t
 he University of Verona. During his years at GSK he took on roles of incre
 asing responsibility\, and developed a strong background in MRI\, neurocom
 putation and neuropharmacology\, as well as in the application of translat
 ional approaches to study neuropsychiatric brain disorders.\n\nIn 2010 Ale
 ssandro joined the Istituto Italiano di Tecnologia (first in Pisa\, next i
 n Rovereto)\, where he lead the Functional Neuroimaging Laboratory (https:
 //www.iit.it/it/web/functional-neuroimaging). The lab is equipped with a 7
  Tesla small-animal MRI scanner for in vivo imaging. During his research a
 ctivity\, he has described the circuital substrates modulated by centrally
 -active pharmacological agents in multiple areas of experimental neuroscie
 nce (e.g. schizophrenia\, depression\, drug addiction etc.) and identified
  functional and structural alterations in different rodent models of brain
  pathology. More recently\, he established methods to map functional conne
 ctivity in the mouse brain and to perturb it with cell-type specificity (c
 hemogenetic-fMRI)\, laying the foundations of a novel field of translation
 al research that is now pursued by an increasing number of laboratories. 
 \n\nOur investigations of the mouse functional connectome have identified 
 mouse homologues of the human default-mode (DMN) and salience networks\, a
 llowing to characterize signatures of disrupted connectivity associated to
  several autism-risk genes. His current research is primarily focused on t
 he investigation of the functional architecture of the mammalian brain at 
 the macroscale\, using the mouse as a physiologically-accessible model org
 anism. Leveraging funding from the European Research Council (ERC\, #Disco
 nn)\, we are currently using perturbational approaches (i.e. chemogenetics
 \, optogenetics\, genetic conditioning) to investigate the elusive neural 
 basis of connectivity disruption in developmental disorders such as autism
 \, or schizophrenia. A major goal of our research is to use functional net
 work systems as a novel translational language that can be related to cogn
 itive processes and neuropathological traits across-species.\n\n\nThe Fein
 del Brain and Mind Seminar Series will advance the vision of Dr. William F
 eindel (1918–2014)\, Former Director of the Neuro (1972–1984)\, to constan
 tly bridge the clinical and research realms. The talks will highlight the 
 latest advances and discoveries in neuropsychology\, cognitive neuroscienc
 e\, and neuroimaging.\n\nSpeakers will include scientists from across The 
 Neuro\, as well as colleagues and collaborators locally and from around th
 e world. The series is intended to provide a virtual forum for scientists 
 and trainees to continue to foster interdisciplinary exchanges on the mech
 anisms\, diagnosis and treatment of brain and cognitive disorders.\n\n \n
DTSTART:20230925T170000Z
DTEND:20230925T180000Z
LOCATION:De Grandpre Communications Centre\, Montreal Neurological Institut
 e\, CA\, QC\, Montreal\, H3A 2B4\, 3801 rue University
SUMMARY:POSTPONED - Feindel Brain and Mind Seminar Series: Mechanisms of fM
 RI (dys)connectivity 
URL:/neuro/channels/event/postponed-feindel-brain-and-
 mind-seminar-series-mechanisms-fmri-dysconnectivity-349192
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