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UID:20250709T194138EDT-3521cALJxz@132.216.98.100
DTSTAMP:20250709T234138Z
DESCRIPTION:Title: A Post-Hoc Evaluation of a Sample Size Re-Estimation: Wh
 at Happens in Real Life?\n\nAbstract: Please visit: https://drexel.edu/dor
 nsife/academics/faculty/Leslie%20McClure/The use of adaptive designs has b
 een increasing in randomized clinical trials. Sample size re-estimation is
  a type of adaptation in which nuisance parameters are estimated at an int
 erim point in the trial and the sample size re-computed based on these est
 imates. However\, post-hoc evaluations of adaptations\, including sample s
 ize re-estimations\, have not frequently been performed\, leaving question
 s about the gains that come from utilizing these procedures in practice. I
 n this talk\, I describe the statistical impact of implementing a sample s
 ize re-estimation in the Secondary Prevention of Small Subcortical Strokes
  (SPS3) study and describe the effect of the adaptation on the practical a
 spects of the study.\n
DTSTART:20190205T203000Z
DTEND:20190205T213000Z
LOCATION:Room 24\, Purvis Hall\, CA\, QC\, Montreal\, H3A 1A2\, 1020 avenue
  des Pins Ouest
SUMMARY:Leslie Ain McClure\, PhD\, MS\, Drexel University
URL:/mathstat/channels/event/leslie-ain-mcclure-phd-ms
 -drexel-university-293916
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