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UID:20251105T152224EST-45634GH82I@132.216.98.100
DTSTAMP:20251105T202224Z
DESCRIPTION:You are invited to attend a special seminar hosted by the Insti
 tute of Parasitology.\n\nDr. Thavy Long is currently a Prestige Marie Curi
 e Fellow at the National Institute for Agricultural Research (Toulouse\, F
 rance). She received her PhD in Parasitology and Cellular Biology in 2010 
 at the University of Lille 2 where she characterized the Polo-like kinases
  (Plks) of Schistosoma mansoni and their role in the reproductive organs. 
 In 2012\, she joined the McKerrow and Caffrey labs (UC San Francisco\, UC 
 San Diego) where her research aimed to identify and validate putative targ
 ets for schistosomiasis.\n\nHelminths are important socio-economic organis
 ms\, responsible for major parasitic infections in humans and animals. Con
 firmed resistance recently reported in filarial nematodes to macrocyclic l
 actones and the existence of a single drug\, praziquantel\, to treat schis
 tosomiasis urge the search for novel therapies to supplement the current a
 rsenal. By combining reverse genetic and phenotypic screens\, Dr Long has 
 shown that Polo-like kinase 1 and phosphodiesterase 4 in S. mansoni are po
 tential drug candidates and identified novel anti-schistosomal chemistries
 . Understanding the mechanisms of drug resistance is also crucial to guara
 ntee sustainable parasite control and she is currently studying the putati
 ve role of nuclear receptors in the development of drug resistance.\n
DTSTART:20171006T153000Z
DTEND:20171006T163000Z
LOCATION:R4-047\, Raymond Building\, CA\, QC\, St Anne de Bellevue\, H9X 3V
 9\, 21111 Lakeshore Road
SUMMARY:From a better understanding of helminth biology to therapeutic targ
 et validation : towards a sustainable parasite control
URL:/macdonald/channels/event/better-understanding-hel
 minth-biology-therapeutic-target-validation-towards-sustainable-parasite-2
 70259
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