BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20250811T201101EDT-4075UdUhgU@132.216.98.100 DTSTAMP:20250812T001101Z DESCRIPTION: \n\nPhD Oral Defense of Cristina Ballesteros\, Institute of Pa rasitology\n\nHuman filarial nematode infections caused by Wucheria bancro fti\, Brugia malayi and Brugia timori can lead to lymphatic filariasis (LF )\, and those due to Onchocerca volvulus can lead to onchocerciasis or riv er blindness\, affecting millions of people in tropical and sub-tropical r egions. Brugia malayi has been an excellent model to study human filarial diseases\, in particular by employing culture systems\, the impact of whic h on the parasites is unknown. One of our objectives was to evaluate chang es in gene expression due to in vitro cultivation of Brugia malayi\, as an index of adaptation to removal from the host. We examined the global tran scriptome of this parasite by Illumina sequencing technology from the time the parasites were extracted from jirds in Georgia (USA)\, shipped to Mon treal (Canada)\, and after maintenance for up to 5 days in culture. It was important to assess the effects of culture on the parasite prior to measu ring the effects of exposure to drugs such as ivermectin.\n\nEveryone in t he 9IÖÆ×÷³§Ãâ·Ñ community is welcome to attend a PhD oral defense. Please join u s in celebrating the accomplishments of our PhD candidates.\n\n \n\n \n DTSTART:20160412T174500Z DTEND:20160412T174500Z LOCATION:R3-038\, Raymond Building\, CA\, QC\, St Anne de Bellevue\, H9X 3V 9\, 21111 Lakeshore Road SUMMARY:PhD Oral Defense: Iron Acquisition in the Adult Filarial Nematode B rugia malayi and the Effect of Ivermectin on Heme Binding Proteins and the Transcriptome URL:/macdonald/channels/event/phd-oral-defense-iron-ac quisition-adult-filarial-nematode-brugia-malayi-and-effect-ivermectin-heme -259828 END:VEVENT END:VCALENDAR