BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20250703T031717EDT-7045OT3s81@132.216.98.100 DTSTAMP:20250703T071717Z DESCRIPTION:Alexandra M. Schmidt\, PhD\n Professor of Statistics – Departmen t of Statistical Methods\, Mathematics Institute\,\n Federal University of Rio de Janeiro\, Brazil\n\nHierarchical dynamic models for time series of highly structured biomedical signals\n\nALL ARE WELCOME\n\nAbstract:\n\nTh is talk considers the modelling of a set of temporally correlated signals with multilevel structure. The study is motivated by Raynaud’s phenomenon (RP) which results from blood vessel spasm. Individuals in the study belon g to one of three groups\, two groups showing different forms of RP and a control group. For each individual multiple time series were generated thr ough thermal infrared imaging. These signals represent the temperature of 10 fingertips across time and document the thermal recovery of an individu al from a standardized cold stress. To investigate the recovery temperatur e profiles of individuals from different groups\, we propose a hierarchica l dynamic model with an exponential growth component. For each group\, the model provides estimates of the mean temperatures across time and of the increase in mean temperatures after the cold stress. These estimates allow us to learn how the temperature recovery differs among groups and how cor related the temperatures among fingers are in different groups. Inference is performed under the Bayesian paradigm\, which naturally accounts for un certainty about parameter estimates. Though motivated by the RP study\, th e proposed methodology is generally applicable to more general hierarchica l time-varying outcomes and can accommodate different temporal structures. \n\nBio:\n\nAlexandra M. Schmidt is a Professor of Statistics of the Feder al University of Rio de Janeiro (UFRJ)\, Brazil. Her main areas of researc h are spatial statistics\, spatio-temporal modeling\, dynamic linear model s\, and hierarchical models. Her projects in these areas usually follow th e Bayesian paradigm to perform inference. She completed her doctoral train ing at the University of Sheffield in 2001\, under the supervision of Prof essor Anthony O’Hagan\, worked for one year as a post-doctoral fellow with Professor Alan Gelfand at the University of Connecticut\, and has been wo rking at the Department of Statistical Methods\, UFRJ\, since 2002. She ha s published 29 papers in peer-reviewed journals\, including JRSS Series B\ , JRSS Series C\, Annals of Applied Statistics\, Canadian Journal of Stati stics\, Technometrics\, Environmetrics\, and Test\, and has supervised or co-supervised 9 Ph.D. and 14 M.Sc. students. In 2008 she was awarded with the Abdel El-Shaarawi Young Investigator Award of The International Enviro nmetrics Society (TIES). She is the current President of the International Society for Bayesian Analysis (ISBA)\, and serves as Associate Editor of the Scandinavian Journal of Statistics (2012-)\, Environmetrics (2010-)\, and Stat (2011-). Please visit www.dme.ufrj.br/~alex/ for more details.\n DTSTART:20151201T203000Z DTEND:20151201T213000Z LOCATION:Room 24\, Purvis Hall\, CA\, QC\, Montreal\, H3A 1A2\, 1020 avenue des Pins Ouest SUMMARY:Biostatistics Seminar URL:/epi-biostat-occh/channels/event/biostatistics-sem inar-256593 END:VEVENT END:VCALENDAR