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UID:20250811T182556EDT-5731erTl9W@132.216.98.100
DTSTAMP:20250811T222556Z
DESCRIPTION:Nanoscale engineering is revolutionizing the way we prevent\, d
 etect and treat diseases. Viruses are playing a special role in these deve
 lopments because they can function as prefabricated nanoparticles naturall
 y evolved to deliver cargos to cells and tissues. My laboratory has develo
 ped a library of plant virus-based nanoparticles\; through structure-funct
 ion studies we are beginning to understand how to tailor these materials a
 ppropriately for biomedical applications. Through synthetic biology\, we h
 ave developed virus-based delivery system carrying contrast agent and/or t
 herapeutic cargo enabling molecular imaging and risk stratification as wel
 l as therapeutic applications targeting cancer and cardiovascular diseases
 . Another avenue is the development of virus-like particle platforms for c
 ancer immunotherapy. The idea pursued is an ‘in situ vaccination’ to stimu
 late systemic anti-tumor immunity to treat metastases\, and most important
 ly induce immune memory to protect patients from recurrence of the disease
 . In this lecture\, I will highlight engineering design principles employe
 d to synthesize the next-generation nanotherapeutics using virus-based pla
 tform technology\, and I will discuss the evaluation of such in preclinica
 l models.\n
DTSTART:20170404T170000Z
DTEND:20170404T181500Z
LOCATION:Room 10\, Maass Chemistry Building\, CA\, QC\, Montreal\, H3A 0B8\
 , 801 rue Sherbrooke Ouest
SUMMARY:Chemical Society Seminar: Dr. Nicole F. Steinmetz - From black-eyed
  peas to nanotechnology: engineering plant virus-based therapeutics
URL:/chemistry/channels/event/chemical-society-seminar
 -dr-nicole-f-steinmetz-black-eyed-peas-nanotechnology-engineering-plant-26
 5274
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