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UID:20250820T014117EDT-7210u05kzF@132.216.98.100
DTSTAMP:20250820T054117Z
DESCRIPTION:Abstract:\n\nSuper-resolution microscopy has opened up a new fr
 ontier in which biological structures and behavior can be observed in fixe
 d and live cells with resolutions down to 20-40 nm and below. Examples ran
 ge from protein superstructures in bacteria to bands in axons to details o
 f the shapes of amyloid fibrils\, cell surface sugars\, and much more. Cur
 rent methods development research addresses ways to extract more informati
 on from each single molecule such as 3D position and orientation\, and to 
 assure not only precision\, but also accuracy. Low temperature single-mole
 cule imaging can be combined with cryo-electron microscopy\, too. Still\, 
 it is worth noting that in spite of all the interest in super-resolution m
 icroscopy of extended structures\, even in the “conventional” single-molec
 ule tracking regime where the motions of individual biomolecules are recor
 ded in cellular environments\, much can be learned. Combining super-resolu
 tion imaging of a static structure with 3D tracking of other biomolecules 
 provides a powerful view of cellular dynamics.\n\nBio:\n\nWilliam Esco Moe
 rner (born June 24\, 1953) is an American physical chemist and chemical ph
 ysicist with current work in the biophysics and imaging of single molecule
 s. He is credited with achieving the first optical detection and spectrosc
 opy of a single molecule in condensed phases\, along with his postdoc\, Lo
 thar Kador. Optical study of single molecules has subsequently become a wi
 dely used single-molecule experiment in chemistry\, physics and biology. I
 n 2014\, he was awarded the Nobel Prize in Chemistry.\n
DTSTART:20190924T170000Z
DTEND:20190924T183000Z
LOCATION:Room 10\, Maass Chemistry Building\, CA\, QC\, Montreal\, H3A 0B8\
 , 801 rue Sherbrooke Ouest
SUMMARY:J.T. Donald Lecture: William E. Moerner - Providing 3D for Super-Re
 solution Microscopy and Single-Particle Tracking in Cells with Single Mole
 cules
URL:/chemistry/channels/event/jt-donald-lecture-willia
 m-e-moerner-providing-3d-super-resolution-microscopy-and-single-particle-3
 00385
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