Myostatin is a paracrine myokine that regulates muscle mass in a variety of species, including humans. In this work, they report a functional role for myostatin as an endocrine hormone that directly promotes pituitary follicle-stimulating hormone (FSH) synthesis and thereby ovarian function in mice. Previously, this FSH-stimulating role was attributed to other members of the transforming growth factor-尾 family, the activins. Their results both challenge activin's eponymous role in FSH synthesis and establish an unexpected endocrine axis between skeletal muscle and the pituitary gland.
Published on: 20 Mar 2025
$400,000 will fuel public-private collaboration to discover new disease biomarkers
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A new project co-led by Thomas Durcan, PhD, Director of The Neuro's Early Drug Discovery Unit, and overseen by Mathilde Chaineau, PhD, the EDDU鈥檚 program manager, will receive $400,000 in support from G茅nome Qu茅bec. In partnership with Nardin Nakhla and Armstrong Murira from the Montreal-based company Simmunome, Durcan and听Chaineau will develop a computational model of amyotrophic lateral sclerosis (ALS) on which to test for new biomarkers and therapeutic targets.
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Published on: 17 Mar 2025
March 7, 2024 | Director听Jennifer Welsh听and Marie-Jo毛lle Zahar wrote a new article on The Future of UN Peacekeeping, which was published by . The authors discuss the challenges UN peace operations are facing and the rising expectations.
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Published on: 12 Mar 2025
Mapping immune cell diversity reveals dexamethasone鈥檚 impact on brain cancer immunotherapy
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Swelling caused by brain cancer is a problem that can lead to serious side effects and even death. While controlling swelling is important, a new study shows that a commonly prescribed anti-swelling drug suppresses the immune system for weeks after dosage, inhibiting the body鈥檚 ability to fight the cancer.
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Published on: 26 Feb 2025
February 6, 2025 |听Alumnus Aftab Ahmed MPP'23 wrote about the . "Trump presents a vision of America as weak, exploited, and in need of tougher negotiation. His solution is a hostile realignment to extract more from allies and adversaries alike while offering them less," writes Aftab. He raises concerns about the cost of inaction becoming dreadful as public health and education systems will suffer in aid-dependent nations.
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Published on: 12 Feb 2025
Projects include important research on Parkinson鈥檚, glioblastoma and dementia
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Published on: 10 Feb 2025
The Canadian Institutes of Health Research's has approved 453 research grants for a total investment of approximately $411M, with 131 projects funded in Quebec.
HBHL is proud to announce that 19 HBHL-funded researchers will receive support for nine projects awarded at 9I制作厂免费 and at the Douglas Research Centre.
HBHL-funded PIs are bolded in the following table:
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Published on: 30 Jan 2025
January 22, 2025 |听Alumnus Aftab Ahmed MPP'23 wrote about growing as social media applications such as Facebook, Messenger, Instagram, Threads and WhatsApp听command听over three billion active monthly users worldwide. In the Policy Magazine, he wrote "Meta faces no competition capable of challenging its influence.
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Published on: 23 Jan 2025
December 21, 2024 |听Norman Hillmer (Slater Visiting Scholar) and Vincent Rigby co-edited with Phil Legasse from NPSIA, book named听.听The book听includes articles by Jennifer Welsh on听Choices for Canada in a New Geopolitical
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Published on: 14 Jan 2025
January 13, 2025 |听Alumnus Anil Wasif MPP'21 wrote an听 as Canada braces for U.S. tariff threats of 25% after the newly elected Trump administration. The strategies disparity between the federal and provincial governments poses a greater problem.听
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Published on: 14 Jan 2025
It is with deep sadness that we remember Emil Skamene, a pioneer in genetic research at 9I制作厂免费.听
His groundbreaking work on host genetic susceptibility to infections has shaped the field for over three decades.
Skamene鈥檚 legacy continues to inspire scientists, including D2R鈥檚 Chief Scientific Officer, Philippe Gros, who, alongside Professor听Erwin Schurr, honors him in a heartfelt eulogy published in Nature Genetics.
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Published on: 6 Jan 2025
Academic and industry scientists collaborate on a new method to characterize research antibodies
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Published on: 18 Dec 2024
First Hybrid Workshop on Precision Health and Medicine
Synergizing our strengths in new technologies in omics, digital sciences, and translational medicine to advance patient care.
This event is organized in partnership between University of Bern and 9I制作厂免费. This partnership between the universities aims to synergistically harness the power of new technologies in omics, digital sciences, and translational medicine to advance patient care.
Event details:听
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Published on: 25 Nov 2024
YCharOS antibody characterization platform addresses the 鈥渞eproducibility crisis鈥� in research
An innovative research project led by researchers at The Neuro has been awarded $1.5M by the Government of Quebec through CQDM.
YCharOS is an innovative platform led by neuroscientists Peter McPherson and Carl Laflamme that validates antibody reagents for human proteins.
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Published on: 12 Nov 2024
Dear Colleagues,
Please see the next Medical Genetics Grand Rounds scheduled talk below:
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Published on: 12 Nov 2024
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