BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20251123T105615EST-67669Wvvbp@132.216.98.100 DTSTAMP:20251123T155615Z DESCRIPTION:Using Machine Learning Methods to Predict Tuberculosis Treatmen t Resistance.\n\nMachine-learning algorithms are used to detect complex\, often unforeseen patterns within rich datasets. There are two general cate gories of algorithms: unsupervised and supervised. Supervised machine-lear ning algorithms\, the topic of this presentation\, start out with a hypoth esis and categories that are set out in advance. These algorithms are then “trained” on data for which the outcomes of interest are known\, with the training process continuing until a desired level of accuracy is achieved . These results are then used to make predictions based on out-of-sample d ata for which the outcome of interest is not known. While most statistical models can be viewed as a simpler form of machine-learning algorithm that imposes a pre-determined functional form for the relationship between the predictors and the outcome of interest\, more advanced machine-learning a lgorithms impose much less structure and can therefore detect very complex and intricate relationships in high-dimensional data (i.e.\, data with se veral different types of variables\, possibly including quantitative\, tex t and image information). Advances are now being made in analyzing the out put of these algorithms to permit assessment of the relative importance of each variable. The current talk will provide an introduction to neural ne tworks\, an advanced supervised machine learning method. The methodology i s then applied to lab data from the World Health Organization (WHO) to ide ntify gene mutations associated with resistance to tuberculosis treatment that are amenable to targeted drug therapy.\n DTSTART:20161025T193000Z DTEND:20161025T203000Z LOCATION:Room 24\, Purvis Hall\, CA\, QC\, Montreal\, H3A 1A2\, 1020 avenue des Pins Ouest SUMMARY:Jimmy Royer\, Analysis Group URL:/channels/event/jimmy-royer-analysis-group-263579 END:VEVENT END:VCALENDAR