9I制作厂免费

Protein folding can be described by the Langevin dynamics. This dynamics can in turn 聽be represented by a 鈥減ath integral鈥�, which is a weighted sum over all paths joining the denatured state with the native state of the protein. We show how one can compute the dominant paths (paths with largest weight) and how one can calculate dynamical quantities such as rates or transition path times from these paths. The method is illustrated on various simple examples.