BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4//
BEGIN:VEVENT
UID:20251127T233602EST-2538ZEVd7V@132.216.98.100
DTSTAMP:20251128T043602Z
DESCRIPTION:Waddington Landscapes in the Age of Machine Learning\n\nPaul Fr
 ancois\, Universite de Montreal\n	Tuesday December 2\, 12-1pm\n	Zoom Link: h
 ttps://mcgill.zoom.us/j/87078928687\n	In Person: 550 Sherbrooke\, Room 189
 \n	\n	Abstract: Waddington’s epigenetic landscape remains a central concept 
 in developmental biology\, illustrating how cells follow robust\, canalize
 d paths toward distinct fates. Despite the rise of high-resolution techniq
 ues like single-cell RNA sequencing\, translating these data into actual l
 andscapes remains a major challenge. In this talk\, I will introduce EvoSc
 ape\, a biologically motivated framework that constructs pseudo-landscapes
  reflecting key properties of differentiation. EvoScape blends concepts fr
 om biophysics and machine learning to produce intuitive\, mechanistic mode
 ls of developmental trajectories. I will illustrate how EvoScape can gener
 ate abstract models of vertebrate segmentation\, and—more concretely—how i
 t reconstructs a landscape of neuromesodermal differentiation directly fro
 m single-cell data\, revealing a structure consistent with known developme
 ntal dynamics. Finally\, I will explore how learning dynamics in Generalis
 ed Hopfield Networks themselves exhibit Waddington-like behaviors\, pointi
 ng to intriguing parallels between biological and computational learning.
 \n
DTSTART:20251202T170000Z
DTEND:20251202T180000Z
SUMMARY:QLS Seminar Series - Paul Francois
URL:/centre-montreal/channels/event/qls-seminar-series
 -paul-francois-369293
END:VEVENT
END:VCALENDAR