BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20251221T183431EST-27870EA6NU@132.216.98.100 DTSTAMP:20251221T233431Z DESCRIPTION:Title: “Mechanotransduction through integrins: basic mechanisms and roles in vascular disease”\n\n \n\nMartin Schwartz\, PhD\n\nYale Univ ersity\n Professor of Medicine (Cardiology)\n Professor of Biomedical Engine ering and of Cell Biology\n Hosted by: Dr. Dieter Reinhardt\n\n \n\nWednesd ay\, Oct 7\, 2020 at 11:30 am\n\nZoom: https://mcgill.zoom.us/j/9542425591 9\n\nMeeting ID: 954 2425 5919\n\n \n\nCells sense the biochemical and bio physical properties of their extracellular matrix environment through inte grin-mediated adhesions. The resultant signals play major roles in guiding development\, physiology\, and normal tissue remodeling required for home ostasis.  Conversely\, altered integrin-dependent signals contribute to pa thological tissue remodeling in cancer\, fibrosis\, atherosclerosis\, and aneurysms.  I will present our recent work toward understanding fundamenta l\, biophysical mechanisms of force transmission and mechanotransduction t hrough integrins\, and the roles of matrix remodeling and integrin signali ng in vascular disease.\n\n \n\n \n DTSTART:20201007T153000Z DTEND:20201007T163000Z LOCATION:https://mcgill.zoom.us/j/95424255919 SUMMARY:Seminar - Anatomy & Cell Biology - Dr Martin Schwartz (Yale) URL:/anatomy/channels/event/seminar-anatomy-cell-biolo gy-dr-martin-schwartz-yale-324767 END:VEVENT END:VCALENDAR